How to get from Prague to Brussels
- 719 km as the crow flies
- Fastest: bus, 13h 20m
- 18 bus departures a day with FlixBus
Compare the train, bus and flight options. Then check them for your own date.
At a glance
Fastest
13h 20m
direct
Bus
€52
Calculated by Routavio, refreshed 5 Oct 2026
Start with the whole journey.
We compared the ways to travel from Prague to Brussels. The most useful door-to-door route takes 13h 20m by bus with no transfer. The two cities are about 719 km apart in a straight line. The price and operators below come from a real route search.
The lowest we recorded in the last 14 days was €27, on Tue, Sep 22.
719 km
Which way suits you?
| Transport | Observed fare | Duration and scope | Detail |
|---|---|---|---|
| Flight | €17Checked Oct 5 | 1h 41mFlight only | See Flight details |
| Bus | €43Omio catalogue, Oct 5 | 13h 20mdirect | See Bus details |
- Flight€17Checked Oct 51h 41m · Flight onlySee Flight details
- Bus€43Omio catalogue, Oct 513h 20m · directSee Bus details
These figures were observed on different days. This table is not a live price ranking for your date.
Prague to Brussels: cheapest or fastest?
All from the same recent search. Pick a tab: the legs, the timing and the difference from the others all change with it.
- 1Praha hlavní nádraží → Bruxelles Midibus
FlixBus·13h 20m
The best balance of price and time we found on this route.
The observed fares belong to earlier dates.
Search my dateWhich date should you go?
The amounts on each day are fares seen earlier, not live offers. A day with no figure is one we have not priced, not one without a service.
All transport observations
Flight calendar
Flight prices by day, Prague to Brussels
The lowest fare we saw for each day over the next three months. Tap a day to search it live.
October 2026
€17November 2026
€31Departures from Prague to Brussels
FlixBus runs 18 scheduled departures a day, the first at 01:25 and the last at 23:05.
| Operator | Departures a day | First | Last |
|---|---|---|---|
| FlixBusbus | 18 | 01:25 | 23:05 |
All departures
- 01:25
- 01:40
- 02:25
- 02:40
- 03:25
- 08:30
- 08:35
- 09:00
- 09:05
- 09:35
- 10:05
- 11:00
- 14:15
- 15:15
- 16:15
- 21:05
- 22:05
- 23:05
Departure times come from operator timetables and are local time at the origin. Where a row shows no times, the frequency is the operator's own and the timetable is not published to us. Times can change on holidays and at short notice; confirm with the operator before you travel.
Departure and arrival
Ticket prices on this route
What each way of travelling costs, as the operator publishes it. These describe the route rather than a date you pick, and they refresh once a day. Booking opens at our partner Omio.
Omio last refreshed these on Mon, Oct 5
Operators seen on these journeys
On this route you travel with FlixBus; Routavio does not add a booking fee.
How the trip from Prague to Brussels works
Start with a FlixBus bus from Praha hlavní nádraží to Bruxelles Midi, about 13h 20m. In total it's roughly €52 over 13h 20m, direct, no transfers.
Prague to Brussels: common questions
How long does it take to get from Prague to Brussels?
The most useful route takes about 13h 20m by bus, with no transfer.
When is the first bus from Prague to Brussels?
The first bus with FlixBus leaves at 01:25 and the last at 23:05, from Praha hlavní nádraží, according to the published timetable.
How many bus departures a day are there from Prague to Brussels?
18 a day with FlixBus, between 01:25 and 23:05.
Which station does the bus from Prague to Brussels leave from?
Praha hlavní nádraží with FlixBus, according to the published timetable.
How far is Brussels from Prague?
About 719 km in a straight line. The real route on the ground or in the air is longer.
How much does Prague to Brussels cost?
On the upcoming dates we checked, the cheapest fare ranged from €41 to €52. Run a live search for your own date to see today's price.
Which operators run Prague to Brussels?
On this route you travel with FlixBus.
Can you get from Prague to Brussels without flying?
Yes. A ground route by train takes about 11h 04m.
What is the cheapest way to get from Prague to Brussels?
Usually a flexible date, or leaving from a nearby airport. A live search puts every option for your dates side by side.
Can I book directly?
Yes. Routavio sends you straight to the operator or an independent third-party provider. We never add a booking fee. The final fare and availability are confirmed by that provider.
Other ways people search Prague to Brussels
- how to get from Prague to Brussels
- Prague to Brussels travel time
- Prague to Brussels distance
- cheapest way from Prague to Brussels
- Prague to Brussels by bus
Sources and method
Routes are calculated by Routavio's multimodal engine from operator timetables and flight data. Durations come from timetables, and prices are the most recent observation, not a guarantee.
Operators: FlixBus
Route calculated: 5 Oct 2026